Research

Folkhälsan Research Center

One of the main fields of focus at Folkhälsan is scientific research. The Folkhälsan Research Center, responsible for Folkhälsan’s research activities, is an internationally renowned unit with focus on biomedical and health research within programs on genetics and public health.

The Center operates in Biomedicum Helsinki in the medical campus of the University of Helsinki and in Folkhälsan’s main building near the medical campus. The Center accommodates a staff of approximately 200. The total funding for 2023 was 9.7 million euros, of which external financing accounted for 45 percent. Read our Annual Report here.

Administration

The Board of the Research Center is responsible for coordinating the overall activities within the Center.

Board Members:

Tom Böhling (Chair)
Christel Gripenberg-Lerche (Vice Chair)
Kristian Wahlbeck 
Niklas Talling

Secretary: Michael von Boguslawski
Presenter: Anna-Elina Lehesjoki 

Presence right:
Johan Eriksson
Siv Sandberg

The Operational Board of the Center supports the Director of the Center in coordinating the research programs and in promoting their collaboration.

Board Members:

Anna-Elina-Lehesjoki (Chair) 
Michael von Boguslawski 
Outi Elomaa
Johan Eriksson
Markku Lehto
Eva Roos
Niina Sandholm
Marco Savarese
Heli Viljakainen
Jaana Welin-Haapamäki (Secretary)

Presence right:
Heidi Furu

Folkhälsan Research Center is part of Samfundet Folkhälsan i svenska Finland rf. The Research Center is financed partly by Samfundet Folkhälsan's own funds and support from the Folkhälsan Research Foundation, and partly by external grants.

Director: Anna-Elina Lehesjoki

Administrative Manager: Michael von Boguslawski

Compliance Expert: Outi Elomaa

Science Communicator: Heidi Furu

Executive Assistant: Jaana Welin-Haapamäki

Planner: Carina Brandstetter

Financial Manager: Nina Forss

Economic Administrator: Sebastian Oey

Director: Markku Lehto

Laboratory Manager: Ann-Liz Träskelin

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Ossian Schauman, one of the founders and the first chairman of Folkhälsan, and  his wife Betsy left in their will almost their entire property to "establish and maintain a Swedish institute for theoretical and applied genetic research". The Folkhälsan Institute of Genetics was founded in 1962. The first two decades it operated in close cooperation with the Medical Research Institute Minerva, later also with the Department of Medical Genetics of the University of Helsinki.

In 1990s Folkhälsan decided to broaden its research activities to encompass also public health related research. The Folkhälsan Research Centre was founded in 1994, and in 1997 the Center moved to its own premises in the Folkhälsan Senior House at Mannerheimintie 97. Since 2001 the major part of the Center has been located in Biomedicum Helsinki. The genetic research and the administration of the Research Center are located in the Biomedicum.

The public health research teams work in Folkhälsan main building, Topeliuksenkatu 20, Helsinki.

The Center has close collaboration with the University of Helsinki, which is based on a mutual cooperation agreement since 1996. Many of the Group Leaders in the Center are professors at the University of Helsinki. Five research groups are affiliated with the Research Programs of the Medical Faculty, University of Helsinki for the period 2019-2025: Groups Groop, Mäkitie and Tuomi within the Clinical and Molecular Metabolism Research Program and Groups Kere, and Kallijärvi within the Stem Cells and Metabolism Research Program. Anna-Elina Lehesjoki and Hannes Lohi work as HiLIFE Fellows at the Helsinki Institute of Life Science (HiLIFE) at the University of Helsinki in 2017–2020.

2024

Salla Mikkola: Feline personality and problematic behaviour – Associations with demographic, genetic, and environmental factors. 2024.

Rebecka Ventin-Holmberg: Biomarkers of the gut fungal and bacterial composition in inflammatory bowel disease. 2024.

Pinja ElomaaSimple devices for single-cell trapping and droplet digital PCR. 2024.

Viivi Saari: Growth, puberty, gynecological health, and fertility in women with APECED. 2024.

Cedric Korpijaakko: Cardiometabolic health and morbidity in offspring of women with type 1 diabetes. 2024.

2023

Joonatan BorchersPrimary adrenal insufficiency: epidemiological aspects and associating features in APECED. 2023.

Perttu LiuskaMyocilin and the genetics of open-angle glaucoma in Finland. 2023.

Jenny WadénsRAGE and genetic variations at the HLA locus in type 1 diabetes, its complications, and mortality. 2023.

Niina-Maria NissinenSecondary disabilities in Finnish youth with prenatal substance exposure. 2023. 

Mari LaaksoFlourishing students and families – Enhancing well-being of adolescents and families through positive psychology interventions. 2023.    

Maria Enlund-CerulloVitamin D metabolism in early childhood; associations with genetic variants and biomarkers. 2023. 

Eduard Daura SarrocaRole of cystatin B in the regulation of histone H3 tail proteolysis in the mouse brain : study on the molecular mechanisms of progressive myoclonus epilepsy type 1. 2023.

Riikka PajulahtiIndividual perspective on the world of food: Studies on temperament, food environment, and diet among children. 2023.            

Elina TuovinenPhenotypic and mechanistic clues to inborn errors of immunity. 2023.

Mia ErikssonMelancholia or Not; The Mysterious Differences in Depression: A Study of Pathophysiological Differences Between Depressive Subtypes – Findings from The Helsinki Birth Cohort Study. 2023

Sini SulkamaRisk factors of canine ADHD-like and repetitive behaviour. 2023

2022

Marjo NuottamoMigraine with aura – genetic susceptibility variants. 2022

Emma DahlströmObesity and complications in type 1 diabetes  – a genetic and clinical perspective. 2022

Lydia SagathCopy number variants in genes causing neuromuscular disorders. 2022

Claudia OttkaMetabolomics in canine physiology and pathophysiology: A nuclear magnetic resonance (NMR) spectroscopy method for dogs. 2022

Fanny Jansson SiegfriedsIncidence, progression, and regression of diabetic kidney disease in type 1 diabetes. 2022

Julia NiskanenThe genetic background of five canine models of rare human disease. 2022

Sohvi LommiSweet treat consumption in school-aged children – Relationships to excess weight, dental caries and saliva microbiota. 2022 

2021             

Petra LoidGenetic determinants of severe childhood-onset obesity. 2021

Stefanie Hägg-HolmbergIncidence, risk factors, and prognosis of stroke in people with type 1 diabetes. 2021

Nicolae Mircea PanduruUrinary biomarkers for the prediction of diabetic nephropathy, cardiovascular disease and mortality in individuals with type 1 diabetes.

2021

Johan Rasmus Alexander SimonsenBacterial infections in type 1 diabetes and their association with micro- and macrovascular complications. 2021

Jarno KettunenThe FINNMODY study : clinical characterization of maturity-onset diabetes of the young (MODY) in Finland. 2021

Anna SyreeniGenetic aspects of type 1 diabetes and its complications. 2021

Mridul JohariMolecular Genetics of Inclusion Body Myositis and Late-Onset Rimmed-Vacuolar Distal Myopathy. 2021

2020           

Riikka SarviahoGenetics of Canine Epilepsy and Anxiety. 2020

Salla VälipakkaImproving CNV detection from short-read MPS data in neuromuscular disorders. 2020

Janne PurhonenMolecular, metabolic, and therapeutic aspects of respiratory complex III deficiency: Bcs1l mutant mice as an experimental model. 2020

Milla SalonenComplex traits, complex results: The genetic, demographic, and environmental factors of cat and dog behaviour. 2020

Heidi Tikkanen-DolencPhysical activity and Type1 diabetes: Impact on diabetic complications. 2020

Meharji ArumilliBioinformatic approaches to facilitate canine disease genetics and genomics. 2020

Maija FeodoroffRole of alcohol and smoking for vascular complications in Type 1 diabetes. 2020 

2019           

Jayasimman RajendranInterventions to improve mitochondrial function in a mouse model of GRACILE syndrome, a complex III disorder. 2019

Svetlana VakkilainenImmunodeficiency in cartilage-hair hypoplasia: Correlation with pulmonary disease, infections and malignancy. 2019

Jenni LaitilaElucidating nebulin expression and function in health and disease

Maria KaukonenGenetics of three canine eye disorders. 2019

2018             

Riikka MäkitieSkeletal and extra-skeletal characteristics of WNT1 osteoporosis. 2018

Mari MuurinenSilver-Russell syndrome and human genetics: genetic and epigenetic studies. 2018

Jenni PuurunenMetabolomic characterization of canine behavioural disorders: fearfulness and hyperactivity/impulsivity. 2018

2017

Christopher L. FogartyBiological factors involved in the modulation of bacterial endotoxin-mediated inflammation in type 1 diabetes. 2017

Satu MassinenSpecific readning disorder: cellular and neurodevelopmental functions of susceptibility genes. 2017

Inken KörberMicroglial dysfunction in Cstb-/- mice, a model for the neurodegenerative disorder progressive myoclonus epilepsy of Unverricht-Lundborg type, EPM1. 2017 

2016

Elviira LehtoThe associations between schoolchildren s fruit and vegetable intake and psychosocial factors – shaped by gender, socioeconomic background and an intervention. 2016

Anni EviläNovel genetic defects in titinopathies and other muscular dystrophies. 2016 

Mikko MuonaIdentification of new genetic syndromes with epilepsy by whole-exome sequencing. 2016

Hanna Paatela: Role of dehydroepiandrosterone in high-density lipoprotein-mediated vasodilation and in adipose tissue steroid biosynthesis. 2016

Mariann LasseniusBacterial endotoxins in type 1 diabetes. 2016 

Our Research Center

Contact

    • Anna-Elina Lehesjoki

      MD, PhD, Professor, Group Leader

    • Tel:
      +358 50 5058894

    • Contact
    • Jaana Welin-Haapamäki

      Executive Assistant

    • Tel:
      +358 50 539 5194

    • Contact