Seniorforskare

Heli Pessa, PhD

Katarzyna Leskinen, PhD

Doktorander

Tiira Johansson, MSc

Pinja Elomaa, MSc

Rebecka Ventin-Holmberg, MSc

Samineh Barmaki, MSc

Enhanced influenza A H1N1 T cell epitope recognition and cross-reactivity to protein-O-mannosyltransferase 1 in Pandemrix-associated narcolepsy type 1.
Vuorela A, Freitag TL, Leskinen K, Pessa H, Härkönen T, Stracenski I, Kirjavainen T, Olsen P, Saarenpää-Heikkilä O, Ilonen J, Knip M, Vaheri A, Partinen M, Saavalainen P, Meri S, Vaarala O. Nature Communications. 2021. 

Clustering based approach for population level identification of condition-associated T-cell receptor β-chain CDR3 sequences. 
Yohannes DA, Kaukinen K, Kurppa K, Saavalainen P, Greco D. BMC Bioinformatics. 2021. 

Targeted RNA-Based Oxford Nanopore Sequencing for Typing 12 Classical HLA Genes. 
Johansson T, Koskela S, Yohannes DA, Partanen J, Saavalainen P. Frontiers in Genetics. 2021.

HLA RNA Sequencing With Unique Molecular Identifiers Reveals High Allele-Specific Variability in mRNA Expression.
Johansson T, Yohannes DA, Koskela S, Partanen J, Saavalainen P.  Frontiers in Immunology. 2021. 

Effects of In Vivo Gluten Challenge on PBMC Gene Expression Profiles in Diet Treated Celiac Disease.
Yohannes DA, de Kauwe A, Kaukinen K, Kurppa K, Mäki M, Anderson RP, Linnarsson S, Greco D, Saavalainen P.  Frontiers in Immunology. 2020.

Bacterial and Fungal Profiles as Markers of Infliximab Drug Response in Inflammatory Bowel Disease. 
Ventin-Holmberg R, Eberl A, Saqib S, Korpela K, Virtanen S, Sipponen T, Salonen A, Saavalainen P, Nissilä E. J Crohns Colitis. 2021.

The psoriasis risk allele HLA-Cw*06:02 shows evidence of association with chronic or recurrent streptococcal tonsillitis.
Haapasalo K, Koskinen LLE, Suvilehto J, Jousilahti P, Wolin A, Suomela S, Trembath R, Barker J, Vuopio J, Kere J, Jokiranta S, Saavalainen P. Infection and Immunity. 2018. 

Deep sequencing of blood and gut T-cell receptor β-chains reveals gluten-induced immune signatures in celiac disease. 
Yohannes DA, Freitag TL, de Kauwe A, Kaukinen K, Kurppa K, Wacklin P, Mäki M, Arstila TP, Anderson RP, Greco D, Saavalainen P. Scientific Reports. 2017. 

A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis. 
Rivas MA, Graham D, Sulem P, Stevens C, Desch AN, Goyette P, Gudbjartsson D, Jonsdottir I, Thorsteinsdottir U, Degenhardt F, Mucha S, Kurki MI, Li D, D'Amato M, Annese V, Vermeire S, Weersma RK, Halfvarson J, Paavola-Sakki P, Lappalainen M, Lek M, Cummings B, Tukiainen T, Haritunians T, Halme L, Koskinen LL, Ananthakrishnan AN, Luo Y, Heap GA, Visschedijk MC; UK IBD Genetics Consortium; NIDDK IBD Genetics Consortium, MacArthur DG, Neale BM, Ahmad T, Anderson CA, Brant SR, Duerr RH, Silverberg MS, Cho JH, Palotie A, Saavalainen P, Kontula K, Färkkilä M, McGovern DP, Franke A, Stefansson K, Rioux JD, Xavier RJ, Daly MJ, Barrett J, de Lane K, Edwards C, Hart A, Hawkey C, Jostins L, Kennedy N, Lamb C, Lee J, Lees C, Mansfield J, Mathew C, Mowatt C, Newman B, Nimmo E, Parkes M, Pollard M, Prescott N, Randall J, Rice D, Satsangi J, Simmons A, Tremelling M, Uhlig H, Wilson D, Abraham C, Achkar JP, Bitton A, Boucher G, Croitoru K, Fleshner P, Glas J, Kugathasan S, Limbergen JV, Milgrom R, Proctor D, Regueiro M, Schumm PL, Sharma Y, Stempak JM, Targan SR, Wang MH. Nature Communications. 2016.

Multiple common variants for celiac disease influencing immune gene expression.
Dubois P,  Trynka G, Franke L, Hunt K, Romanos J, Curtotti A, Zhernakova A, Heap G, Adany R, Aromaa A, Bardella M, van den Berg, L, Bockett N, de la Concha E, Dema B, Fehrmann R, Fernandez-Arquero M, Fiatal S, Grandone E, Green P, Groen H, Gwilliam R, Houwen R, Hunt S, Kaukinen K, Kelleher D, Korponay-Szabo I, Kurppa K, MacMathuna P, Mäki M, Mazzilli M, McCann P, Mearin M, Mein C, Mirza M, Mistry V, Mora B, Morley K, Mulder C, Murray J, Nunez C, Oosterom E, Ophoff R, Polanco I, Peltonen L, Platteel M, Rybak A, Salomaa V, Schweizer J, Sperandeo M, Tack G, Turner G, Veldink J, Verbeek W, Weersma R, Wolters V, Urcelay E, Cukrowska B, Greco L, Neuhausen S, McManus R, Barisani D, Deloukas P, Barrett J,  Saavalainen P, Wijmenga C, van Heel D.  Nature Genetics. 2010.

Celiac Disease Research Center, University of Tampere: Katri Kaukinen, Katri Lindfors, Kalle Kurppa, Teea Salmi, Markku Mäki

Inflammatory Bowel Disease Research Group, University of Helsinki and HUS: Taina Sipponen, Anja Eberl, Martti Färkkilä

Ovarian cancer research: Seppo Meri, Sampsa Hautaniemi, University of Helsinki

Folkhälsans forskningsstiftelse

Finlands Akademi

Business Finland

Sigrid Jusélius Stiftelse